- Swellings or lumps that do not disappear
- Wounds that do not heal
- Weight loss
- Loss of appetite
- Abnormal bleeding or discharge (e.g. from the nose)
- Unpleasant odor (e.g. from the mouth)
- Trouble swallowing or chewing
- Loss of energy or stamina
- Abnormal stiffness or limping
- Difficulties breathing or urinating/defecating